3,3-Diphenylcyclobutanamine

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3,3-Diphenylcyclobutanamine
Systematic (IUPAC) name
3,3-diphenylcyclobutan-1-amine
Clinical data
Legal status Uncontrolled
Identifiers
ATC code None
PubChem CID 47486
ChemSpider 43204 YesY
Chemical data
Formula C16H17N 
Mol. mass 223.31 g/mol
 YesY (what is this?)  (verify)

3,3,-Diphenylcyclobutanamine is a psychostimulant drug which was originally prepared as an antidepressant in the late 1970s.[1] It appears to inhibit the reuptake of serotonin, norepinephrine, and dopamine, and may also induce their release as well.[1] The N-methyl and N,N-dimethyl analogues of the compound are also known and are more potent.[1] All three agents produce locomotor stimulation in animal studies, with the tertiary amine being the strongest.[1]

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References[edit]

  1. ^ a b c d Carnmalm B, Rämsby S, Renyi AL, Ross SB, Ogren SO (January 1978). "Antidepressant agents. 9. 3,3-Diphenylcyclobutylamines, a new class of central stimulants". Journal of Medicinal Chemistry 21 (1): 78–82. doi:10.1021/jm00199a014. PMID 22757.