From Wikipedia, the free encyclopedia
|Systematic (IUPAC) name|
|CAS Number||1400742-68-8 (racemic)
1364331-88-3 (R, R absolute stereochemistry)
|Molar mass||302.196 g/mol|
|(what is this?)|
3,4-Dichloromethylphenidate is a stimulant drug related to methylphenidate. Dichloromethylphenidate is a potent psychostimulant that acts as both a dopamine reuptake inhibitor and norepinephrine reuptake inhibitor, meaning it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters in the brain, by binding to, and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft
3,4-CTMP, the threo-diastereomer, is approximately seven times more potent than methylphenidate in animal studies, but has weaker reinforcing effects due to its slower onset of action. However, H. M. Deutsch's discrimination ratio implies it to be more reinforcing than cocaine.
As of October 2015 3,4-CTMP is a controlled substance in China.
Sweden's public health agency suggested to classify 3,4-CTMP as hazardous substance on November 10, 2014.
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