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3-(p-Fluorobenzoyl)tropane

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3-(p-Fluorobenzoyl)tropane
Systematic (IUPAC) name
(1R,5S)-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-4-fluorobenzoate
Identifiers
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ATC code  ?
PubChem 5147770
Chemical data
Formula C15H18FNO2 
Mol. mass 263.307
SMILES eMolecules & PubChem
Pharmacokinetic data
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Therapeutic considerations
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3-(p-Fluorobenzoyl)tropane, (4-fluorotropacocaine, 3-pseudotropyl-4-fluorobenzoate, pFBT) is a tropane derivative drug which acts as a stimulant and local anaesthetic, having around 30% the stimulant potency of cocaine but around the same potency as a local anaesthetic.[citation needed] It has been investigated as a potential radiolabelled agent for studying receptor binding,[1] and as a potential neuroleptic drug,[2] but was not adopted for either of these applications.

References

  1. ^ Ali M. Emran. New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control. Springer, 1991. p84. ISBN 0306440350
  2. ^ Fontenla JA, Cadavid MI, Orallo F, Eirin A, Calleja JM. Synthesis and study of the possible neuroleptic activity of 3-(p-fluorobenzoyl)-tropane. Archivos de Farmacologia y Toxicologia. (Spanish) 1984 Dec;10(3):151-60. PMID 6152386

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