ABT-670

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ABT-670
Systematic (IUPAC) name
3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 630119-43-6 N
ATC code  ?
PubChem CID 16094676
ChemSpider 17252978 YesY
UNII 4L6071XH2J N
ChEMBL CHEMBL219182 YesY
Chemical data
Formula C19H23N3O2 
Mol. mass 325.404 g/mol
 N (what is this?)  (verify)

ABT-670 is a drug which acts as a potent, orally bioavailable dopamine agonist selective for the D4 subtype, which was developed as a possible treatment for erectile dysfunction,[1] although its current uses are limited to scientific research.[2]

See also[edit]

References[edit]

  1. ^ Patel, MV; Kolasa, T; Mortell, K; Matulenko, MA; Hakeem, AA; Rohde, JJ; Nelson, SL; Cowart, MD et al. (2006). "Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-2,4'-bipyridine-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction". Journal of Medical Chemistry 49 (25): 7450–65. doi:10.1021/jm060662k. PMID 17149874.  |displayauthors= suggested (help)
  2. ^ Richards N, Wayman C, Allers KA. Electrophysiological actions of the dopamine agonist apomorphine in the paraventricular nucleus during penile erection. Neuroscience Letters. 3 September 2009 doi:10.1016/j.neulet.2009.08.078