Azapride

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Azapride
Azapride.png
Systematic (IUPAC) name
4-Azido-5-chloro-2-methoxy-N-[1-(phenylmethyl)piperidin-4-yl]benzamide
Identifiers
CAS Number 92990-90-4 YesY
ATC code none
PubChem CID 3036441
ChemSpider 2300456 YesY
Chemical data
Formula C20H22ClN5O2
Molar mass 399.87
  (verify)

Azapride is the azide derivative of the dopamine antagonist clebopride synthesized in order to label dopamine receptors.[1][2] It is an irreversible dopamine antagonist.[3]

References[edit]

  1. ^ Niznik HB, Guan JH, Neumeyer JL, Seeman P. (1985) 'A photoaffinity ligand for dopamine D2 receptors: azidoclebopride.', Mol Pharmacol.
  2. ^ Wouters W, Van Dun J, Laduron PM.(1984),'Photoaffinity labelling of dopamine receptors. Synthesis and binding characteristics of azapride.', Eur J Biochem.
  3. ^ European Journal of Biochemistry 1984, 145(2), p.273