CACNG3

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Calcium channel, voltage-dependent, gamma subunit 3

Identifiers

Symbols

CACNG3; Cacng2

External IDs

OMIM: 606403 MGI: 1859165 HomoloGene: 4767

Gene ontology
Molecular function:	• structural molecule activity • voltage-gated calcium channel activity • calcium ion binding
Cellular component:	• voltage-gated calcium channel complex • tight junction • membrane • integral to membrane
Biological process:	• ion transport • calcium ion transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006539 (mRNA)
NP_006530 (protein)

NM_019430 (mRNA)
NP_062303 (protein)

Location

Chr 16: 24.17 - 24.28 Mb

Chr 7: 122.46 - 122.56 Mb

Pubmed search

[1]

[2]

Calcium channel, voltage-dependent, gamma subunit 3, also known as CACNG3, is a human gene.^[1]

L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which have been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family. This gene is a candidate gene for a familial infantile convulsive disorder with paroxysomal choreoathetosis.^[1]

1 See also
2 References
3 Further reading
4 External links

References

^ ^a ^b "Entrez Gene: CACNG3 calcium channel, voltage-dependent, gamma subunit 3".

External links

MeSH CACNG3+protein,+human

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v • d • e

Membrane transport protein: ion channels

Ca²⁺: Calcium channel

Voltage-gated	L-type/Ca_vα (1.1, 1.2, 1.3, 1.4) • N-type/Ca_vα2.2 • P-type/Ca_vα(2.1) • Q-type/Ca_vα2.1 • R-type/Ca_vα2.3 • T-type/Ca_vα(3.2) α₂δ-subunits (1, 2) • β-subunits (β1, β2, β3, β4) • γ-subunits (γ1, γ2, γ3, γ4) Cation channels of sperm • Two-pore channel (1, 2)

Ligand-gated	Inositol triphosphate receptor (1, 2, 3) • Ryanodine receptor (1, 2, 3)

Na⁺: Sodium channel

Voltage-gated	Na_vα (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, 7A) • Na_vβ (1, 2, 3, 4)

Other	Epithelial sodium channel (α, β, γ, δ)

K⁺: Potassium channel

Voltage-gated	K_vα1-6 (1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.10) • (2.1, 2.2) • (3.1, 3.2, 3.3, 3.4) • (4.1, 4.2, 4.3) • (5.1) • (6.1, 6.2, 6.3, 6.4) K_vα7-12 (7.1, 7.2, 7.3, 7.4, 7.5) • (8.1, 8.2) • (9.1, 9.2, 9.3) • (10.1, 10.2) • (11.1/hERG, 11.2, 11.3) • (12.1, 12.2, 12.3) K_vβ (1, 2, 3) • KCNIP (1, 2, 3, 4) • minK/ISK • MiRP (1, 2, 3) • Shaker gene

Calcium-activated	BK channel (α1, β1, β2, β3, β4) • SK channel (SK1, SK2, SK3, SK4)

Inward-rectifier	K_ir (1.1, 2.1, 2.2, 2.3, 2.4) • GIRK/K_ir (3.1, 3.2, 3.3, 3.4) • K_ir (4.1, 4.2, 5.1, 6.1, 6.2, 7.1)

Tandem pore domain	K2P (1, 2, 3, 4, 5, 6, 7, 9, 10, 12, 13, 15, 16, 17, 18)