CP-226,269

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CP-226,269
CP-226269 structure.png
Systematic (IUPAC) name
5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole
Identifiers
CAS Registry Number 220941-93-5 N
PubChem CID: 9796720
IUPHAR/BPS 973
ChemSpider 7972486 YesY
ChEMBL CHEMBL77395 YesY
Chemical data
Formula C18H19FN4
Molecular mass 310.368 g/mol
 N (what is this?)  (verify)

CP-226,269 is a drug which acts as a dopamine agonist selective for the D4 subtype, which is used for researching the role of D4 receptors in the brain.[1][2]

References[edit]

  1. ^ Sharma A, Kramer ML, Wick PF, Liu D, Chari S, Shim S, Tan W, Ouellette D, Nagata M, DuRand CJ, Kotb M, Deth RC (May 1999). "D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia". Molecular Psychiatry 4 (3): 235–46. doi:10.1038/sj.mp.4000522. PMID 10395213. 
  2. ^ Basso AM, Gallagher KB, Bratcher NA, Brioni JD, Moreland RB, Hsieh GC, Drescher K, Fox GB, Decker MW, Rueter LE (July 2005). "Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test". Neuropsychopharmacology 30 (7): 1257–68. doi:10.1038/sj.npp.1300677. PMID 15688083.