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Ciclindole

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Ciclindole
Systematic (IUPAC) name
N,N-dimethyl-2,3,4,9-tetrahydro-1H-carbazol-3-amine
Identifiers
CAS number 32211-97-5
ATC code None
PubChem CID 36082
ChemSpider 33189
Chemical data
Formula C14H18N2 
Mol. mass 214.31 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status Uncontrolled
Routes Oral

Ciclindole (INN; WIN-27,147-2), also known as cyclindole (USAN), is an antipsychotic with a tricyclic structure that was never marketed.[1][2] It displaces spiperone binding in vitro and elevates dopamine levels in the striatum, indicating it acts as a D2 receptor antagonist.[2]

See also

References

  1. ^ David J. Triggle (1996). Dictionary of Pharmacological Agents. Boca Raton: Chapman & Hall/CRC. ISBN 0-412-46630-9. http://books.google.com/books?id=DeX7jgInYFMC&lpg=PA540&dq=cyclindole&as_brr=3&pg=PA540#v=onepage&q&f=false. 
  2. ^ a b Wood PL, McQuade PS (1984). "Ciclindole and flucindole: novel tetrahydrocarbazolamine neuroleptics". Progress in Neuro-psychopharmacology & Biological Psychiatry 8 (4-6): 773–7. PMID 6152347. 



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