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Iodobenzamide

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Iodobenzamide
Identifiers
CAS number 84226-06-2 YesY, 113716-48-6 (123I) YesY, 113452-80-5 (125I) YesY
PubChem 107995
ChemSpider 97107
Jmol-3D images Image 1
Properties
Molecular formula C15H21IN2O3
Molar mass 404.24 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

IBZM (abbreviation for iodobenzamide) is a chemical substance. Pharmaceutically it is a dopamine antagonist and it can be used by nuclear medicine physicians as a radioactive tracer for SPECT where the radioactive isotope is iodine-123 or iodine-125.[1][2] The main purpose of a brain study with IBZM is the differentiation of Parkinson's disease from other neurodegenerative diseases such as Lewy Body dementia and multiple system atrophy.

References

  1. ^ Kung, H. F.; Guo, Y. Z.; Billings, J.; Xu, X.; Mach, R. H.; Blau, M.; Ackerhalt, R. E. (1988). "Preparation and biodistribution of [125I]IBZM: a potential CNS D-2 dopamine receptor imaging agent". Nuclear Medicine and Biology 15 (2): 195–201. PMID 2966782. 
  2. ^ Kung, Hank, F.; Alavi; Chang; Kung; Keyes; Velchik; Billings; Pan et al (1990). "In vivo SPECT imaging of CNS D-2 dopamine receptors: initial studies with iodine-123-IBZM in humans". Journal of Nuclear Medicine 31 (5): 573–579. PMID 2140408. 



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