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|Systematic (IUPAC) name|
|Synonyms||4-hydroxyamphetamine, p-hydroxyamphetamine, alpha-methyltryamine|
|Legal status||Schedule II (US)|
para-Hydroxyamphetamine (PHA), also known as Norpholedrine (Oxamphetamine, Paredrine), 4-hydroxyamphetamine (4-HA), and α-methyltyramine (α-Me-TRA), is a sympathomimetic drug, that is, a drug that stimulates the sympathetic nervous system. When used in eye drops, it dilates the pupil. Norpholedrine is sold in combination with tropicamide under the brand name Paremyd. It occurs as a metabolite of amphetamine.
In 1944, the US Naval Submarine Medical Research Laboratory researched the use of Paredrine to improve adaptation to night vision in submarine personnel. A significant improvement in adaptation was shown in the 17 subjects they tested.
- ^ Shulgin, Alexander (September 26, 2001). "Ask Dr. Shulgin Online: Acacias and Natural Amphetamine". Center for Cognitive Liberty & Ethics. http://www.cognitiveliberty.org/shulgin/adsarchive/acacia.htm. Retrieved 2010-02-18.
- ^ Verplanck, WS (1944). "The effects of paregrine on night vision performance.". US Naval Submarine Medical Research Laboratory Technical Report 42. http://archive.rubicon-foundation.org/8242. Retrieved 2010-02-18.
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