Prolintane

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Prolintane
Prolintane.svg
Systematic (IUPAC) name
1-(1-Benzylbutyl)pyrrolidine
Clinical data
oral, intranasal, rectal
Identifiers
493-92-5 N
N06BX14
PubChem CID 14592
ChemSpider 13930 YesY
UNII EM4YZW677H YesY
Chemical data
Formula C15H23N
217.35 g/mol
 N (what is this?)  (verify)

Prolintane (Catovit, Promotil, Villescon) is a stimulant[1] and norepinephrine-dopamine reuptake inhibitor developed in the 1950s.[2] It is closely related in chemical structure to other drugs such as pyrovalerone, MDPV, and propylhexedrine and it has a similar mechanism of action.[3] Prolintane has a good safety profile and has been used even by the elderly. Prolintane is suitable for use up to once a week. Frequent use will cause it to lose effectiveness. Many cases of prolintane abuse have been reported, albeit mostly in European countries.[4]

See also[edit]

References[edit]

  1. ^ Hollister, L. E.; Gillespie, H. K. (1970). "A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers". The Journal of Clinical Pharmacology 10 (2): 103–109. doi:10.1177/009127007001000205. PMID 4392006.  edit
  2. ^ GB Patent 807835
  3. ^ Nicholson, A. N.; Stone, B. M.; Jones, M. M. (1980). "Wakefullness and reduced rapid eye movement sleep: Studies with prolintane and pemoline". British Journal of Clinical Pharmacology 10 (5): 465–472. doi:10.1111/j.1365-2125.1980.tb01790.x. PMC 1430138. PMID 7437258.  edit
  4. ^ Kyle, P. B.; Daley, W. P. (2007). "Domestic Abuse of the European Rave Drug Prolintane". Journal of Analytical Toxicology 31 (7): 415–418. doi:10.1093/jat/31.7.415. PMID 17725890.  edit