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SKF-38,393

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SKF-38,393
Systematic (IUPAC) name
1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 67287-49-4
ATC code  ?
PubChem CID 1242
ChemSpider 1205
ChEMBL CHEMBL24077 YesY
Chemical data
Formula C16H17NO2
Mol. mass 255.31 g/mol
SMILES eMolecules & PubChem

SKF-38,393 is a synthetic compound of the benzazepine chemical class which acts as a selective D1/D5 receptor partial agonist.[1] It has stimulant and anorectic effects.[2][3]

References

  1. ^ Dubois A, Savasta M, Curet O, Scatton B (September 1986). "Autoradiographic distribution of the D1 agonist [3HSKF 38393, in the rat brain and spinal cord. Comparison with the distribution of D2 dopamine receptors"]. Neuroscience 19 (1): 125–37. doi:10.1016/0306-4522(86)90010-2. PMID 2946980. http://linkinghub.elsevier.com/retrieve/pii/0306-4522(86)90010-2. 
  2. ^ Trampus M, Ferri N, Adami M, Ongini E (April 1993). "The dopamine D1 receptor agonists, A68930 and SKF 38393, induce arousal and suppress REM sleep in the rat". European Journal of Pharmacology 235 (1): 83–7. doi:10.1016/0014-2999(93)90823-Z. PMID 8100197. http://linkinghub.elsevier.com/retrieve/pii/0014-2999(93)90823-Z. 
  3. ^ Cooper SJ, Francis J, Rusk IN (1990). "The anorectic effect of SK&F 38393, a selective dopamine D1 receptor agonist: a microstructural analysis of feeding and related behaviour". Psychopharmacology 100 (2): 182–7. doi:10.1007/BF02244403. PMID 1968277. 

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