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Triflupromazine

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Triflupromazine
Systematic (IUPAC) name
N,N-dimethyl-3-[2-(trifluoromethyl)- 10H-phenothiazin-10-yl]-propan-1-amine
Identifiers
CAS number 146-54-3
ATC code N05AA05
PubChem 5568
DrugBank APRD00465
Chemical data
Formula C18H19F3N2S 
Mol. mass 352.418 g/mol
Therapeutic considerations
Pregnancy cat.  ?
Legal status
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Triflupromazine (Vesprin) is an antipsychotic medication of the phenothiazine class. Among different effects of triflupromazine indication for use of this drug is severe emesis. Due to its potential side effects (triflupromazine has higher risk for side effects than many other antipsychotics) it is not gold standard in antiemetic therapy.

Serious side effects of trifluproamzine can be akathisia and tardive dyskinesia as well as the rare, but potentially fatal, neuroleptic malignant syndrome.

References




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