|在位||紀元前164年11月or12月 – 紀元前161年|
At the outset of the reign of Antiochus V, there was an attempt by the Syrians to quell the Maccabean Revolt in Judea, but this ended in a weak compromise. After a military victory in the Battle of Beth-Zecharia, and the killing of Eleazar Avaran, a brother of Judas Maccabaeus, Lysias was informed that Philip (a confidant of Antiochus IV Epiphanes, who had accompanied this previous king to conquer Mesopotamia, and had been entrusted prior to the death of the king with the upbringing of Antiochus V), was returning to the capital with the other half of the Seleucid army. Lysias felt threatened, and advised Antiochus V to offer peace to the Jews. The Jews accepted; however, in order to ensure they would not rise against them again soon, the Syrian king and regent broke their promise and tore down the walls of Jerusalem before leaving.
Upon reaching their own kingdom, Lysias and Antiochus V found Philip in control of the capital Antiochia, but they defeated him and retook the city and kingdom.
When the Roman senate heard that the Syrian kingdom kept more warships and elephants than allowed by the peace treaty of Apamea made in 188 BC, they sent a Roman embassy to travel along the cities of Syria and attempted to cripple Seleucid military power by sinking the Syrians' warships and hamstringing their elephants. Lysias dared do nothing to oppose the Romans, but his subservience so enraged his Syrian subjects that the Roman envoy Gnaeus Octavius (consul of 165 BC) was assassinated in Laodicea (162 BC).
At this juncture Demetrius escaped from Rome and was received in Syria as the true king. Antiochus Eupator was soon put to death together with his protector Lysias.
- Antiochus V Eupator entry in historical sourcebook by Mahlon H. Smith